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new type Oxymethylene

new type Oxymethylene

A significant step in the development of β adrenergic antagonists was the discovery that an oxymethylene bridge (—OCH 2 —, figure 7) could be inserted into the arylethanolamine structure of pronethalol to produce propranolol. Propranolol is an aryloxypropanolamine, which are more potent β-blockers than arylethanolamines.

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